For COMt sake
So here’s the thing and it’s a bit of a challenge to deliver but I think I am going to describe to you something that you haven’t heard about before.
For those of you who have a cheeky tattoo, can play a musical or multiple instruments without lessons, draw an object that looks like what you see, suffer heightened alertness or anxiety, are a bit quirky, worry about mankind, enjoy spiritually and are tempted to modify reality with alcohol and drugs, you almost certainly have been gifted, from your folks, a less functioning COMt gene variant.
See told you have never heard this before, right.
If you are the chosen one to have VAL meets MET or MET meets MET in a gammeting (sperm meet egg) then your neurotransmitters (in your prefrontal cortex) of the likes of adrenaline and dopamine are a bit more dominant in your consciousness. MedlinePlus have a link, look and learn.
Those people with the VAL-MET or MET-MET combo are represented more in PTSD, biochemical behavioural states such as anxiety, anorexia, bulimia depression, bipolar disorder and others.
Why, because adrenaline and dompamine are the drivers of the flight, fight, connect response and in a situation of challenge these in excess cause the ‘distress’.
VAL-MET and MET-MET COMt variants leaves more of the excitatory stuff around.
My guess is the Stones, Beatles, Gaga, Amy Winehouse are all in the same VAL-MET or MET-MET boat.
You can add to the list, those who excite, delight or disgust you more so than an errant neighbour.
Genghis Khan, Kate Shepard, Abraham Lincoln, Ruby Wax, Arnold Schwarzenegger, Cher and Geoff Bezos have probably negotiated life with the same gene variant paddle.
Megalomaniacs of the likes of like Putin, Trump, Mugabe and Stalin are very likely to have the same variants.
JK Rowling, Shakespeare, Mike King (The Impact of COMT and Childhood Maltreatment on Suicidal Behaviour in Affective Disorders) Ursula Carlson, would have a high chance of the gene variant.
Add to them Picasso, Banksy, Monet, Angus, Michelangelo and other greats and you get the picture.
Told you, interesting stuff. It is in those who lie on the borders of and stretch the human envelope that are the most likely carriers and evolutionarily add to the chances of individual survival and hence survival of the human DNA chain.
Ok, so you want more link look and learn: What Is the COMT Gene? And How Does It Affect Your Health?